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Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function

Metabotropic glutamate receptor 5 (mGluR5) regulates excitatory postsynaptic signaling in the central nervous system (CNS) and is implicated in various CNS disorders. Protein kinase A (PKA) signaling is known to play a critical role in neuropsychiatric disorders such as Parkinson’s disease, schizoph...

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Bibliografische gegevens
Gepubliceerd in:J Neurochem
Hoofdauteurs: Uematsu, Ken, Heiman, Myriam, Zelenina, Marina, Padovan, Júlio, Chait, Brian T., Aperia, Anita, Nishi, Akinori, Greengard, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359654/
https://ncbi.nlm.nih.gov/pubmed/25639954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13038
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