Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model

Despite increasingly successful treatment of pediatric ALL, up to 20% of patients encounter relapse. By current biomarkers, the majority of relapse patients is initially not identified indicating the need for prognostic and therapeutic targets reflecting leukemia biology. We previously described tha...

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Publicat a:Oncotarget
Autors principals: Hasan, Md. Nabiul, Queudeville, Manon, Trentin, Luca, Eckhoff, Sarah Mirjam, Bronzini, Ilaria, Palmi, Chiara, Barth, Thomas, Cazzaniga, Giovanni, te Kronnie, Geertruy, Debatin, Klaus-Michael, Meyer, Lüder Hinrich
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359301/
https://ncbi.nlm.nih.gov/pubmed/25682198
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