Pan-PPAR Modulation Effectively Protects APP/PS1 Mice from Amyloid Deposition and Cognitive Deficits

Alzheimer’s disease (AD) is a neurodegenerative condition that leads to neuronal death and memory dysfunction. In the past, specific peroxisome proliferator-activated receptor (PPAR)γ-agonists, such as pioglitazone, have been tested with limited success to improve AD pathology. Here, we investigated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Kummer, Markus P., Schwarzenberger, Rafael, Sayah-Jeanne, Sakina, Dubernet, Mathieu, Walczak, Robert, Hum, Dean W., Schwartz, Stephanie, Axt, Daisy, Heneka, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359287/
https://ncbi.nlm.nih.gov/pubmed/24838579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8743-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados