Angiogenic Activity of Breast Cancer Patients’ Monocytes Reverted by Combined Use of Systems Modeling and Experimental Approaches

Angiogenesis plays a key role in tumor growth and cancer progression. TIE-2-expressing monocytes (TEM) have been reported to critically account for tumor vascularization and growth in mouse tumor experimental models, but the molecular basis of their pro-angiogenic activity are largely unknown. Moreo...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Guex, Nicolas, Crespo, Isaac, Bron, Sylvian, Ifticene-Treboux, Assia, Faes-van’t Hull, Eveline, Kharoubi, Solange, Liechti, Robin, Werffeli, Patricia, Ibberson, Mark, Majo, Francois, Nicolas, Michäel, Laurent, Julien, Garg, Abhishek, Zaman, Khalil, Lehr, Hans-Anton, Stevenson, Brian J., Rüegg, Curzio, Coukos, George, Delaloye, Jean-François, Xenarios, Ioannis, Doucey, Marie-Agnès
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359163/
https://ncbi.nlm.nih.gov/pubmed/25768678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004050
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