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ACTIVATION OF NRF2 COORDINATES DDAH/PPAR-γ/eNOS PATHWAYS THAT ENHANCE NITRIC OXIDE GENERATION IN HUMAN GLOMERULAR ENDOTHELIAL CELLS
Dimethylarginine dimethylaminohydrolase (DDAH) degrades (ADMA) which inhibits nitric oxide synthase (NOS). Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcriptional factor that binds to antioxidant response elements (ARE) and transcribes many antioxidant genes. Since the promoters of t...
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| Izdano u: | Hypertension |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359100/ https://ncbi.nlm.nih.gov/pubmed/25691623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04760 |
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