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CYTOSOLIC PHOSPHOLIPASE A(2)α IS CRITICAL FOR ANGIOTENSIN II – INDUCED HYPERTENSION AND ASSOCIATED CARDIOVASCULAR PATHOPHYSIOLOGY
Angiotensin II activates cPLA(2)α and releases arachidonic acid from tissue phospholipids which mediate or modulate one or more cardiovascular effects of angiotensin II and has been implicated in hypertension. Since arachidonic acid release is the rate limiting step in eicosanoid production, cPLA(2)...
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| Publicado no: | Hypertension |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359078/ https://ncbi.nlm.nih.gov/pubmed/25667212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04803 |
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