A Novel Retro-Inverso Peptide Inhibitor Reverses Angiotensin Receptor Autoantibody-Induced Hypertension in the Rabbit

Activating autoantibodies to the angiotensin II type 1 receptor (AT1R) have been implicated in hypertensive disorders. We investigated whether AT1R antibodies produced in immunized rabbits will activate AT1R and contribute to hypertension by a direct contractile effect on the vasculature; and if the...

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Publicado en:Hypertension
Main Authors: Li, Hongliang, Kem, David C., Zhang, Ling, Huang, Bing, Liles, Campbell, Benbrook, Alexandria, Gali, Hariprasad, Veitla, Vineet, Scherlag, Benjamin J., Cunningham, Madeleine W., Yu, Xichun
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359052/
https://ncbi.nlm.nih.gov/pubmed/25691619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.05037
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