NOD/SCID-GAMMA Mice Are an Ideal Strain to Assess the Efficacy of Therapeutic Agents Used in the Treatment of Myeloma Bone Disease

Animal models of multiple myeloma vary in terms of consistency of onset, degree of tumour burden and degree of myeloma bone disease. Here we describe five pre-clinical models of myeloma in NOD/SCID-GAMMA mice to specifically study the effects of therapeutic agents on myeloma bone disease. Groups of...

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Veröffentlicht in:PLoS One
Hauptverfasser: Lawson, Michelle A., Paton-Hough, Julia M., Evans, Holly R., Walker, Rebecca E., Harris, William, Ratnabalan, Dharshi, Snowden, John A., Chantry, Andrew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358985/
https://ncbi.nlm.nih.gov/pubmed/25768011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119546
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