A Naturally Occurring Null Variant of the NMDA Type Glutamate Receptor NR3B Subunit Is a Risk Factor of Schizophrenia

Hypofunction of the N-methyl-D-aspartate type glutamate receptor (NMDAR) has been implicated in the pathogenesis of schizophrenia. Here, we investigated the significance of a common human genetic variation of the NMDAR NR3B subunit that inserts 4 bases within the coding region (insCGTT) in the patho...

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Veröffentlicht in:PLoS One
Hauptverfasser: Matsuno, Hitomi, Ohi, Kazutaka, Hashimoto, Ryota, Yamamori, Hidenaga, Yasuda, Yuka, Fujimoto, Michiko, Yano-Umeda, Satomi, Saneyoshi, Takeo, Takeda, Masatoshi, Hayashi, Yasunori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358936/
https://ncbi.nlm.nih.gov/pubmed/25768306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116319
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