Early Onset of Hypersynchronous Network Activity and Expression of a Marker of Chronic Seizures in the Tg2576 Mouse Model of Alzheimer’s Disease

Cortical and hippocampal hypersynchrony of neuronal networks seems to be an early event in Alzheimer’s disease pathogenesis. Many mouse models of the disease also present neuronal network hypersynchrony, as evidenced by higher susceptibility to pharmacologically-induced seizures, electroencephalogra...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bezzina, Charlotte, Verret, Laure, Juan, Cécile, Remaud, Jessica, Halley, Hélène, Rampon, Claire, Dahan, Lionel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358928/
https://ncbi.nlm.nih.gov/pubmed/25768013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119910
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