Large conductance Ca(2+)‐activated K(+) (BK) channels promote secretagogue‐induced transition from spiking to bursting in murine anterior pituitary corticotrophs

KEY POINTS: Corticotroph cells of the anterior pituitary are electrically excitable and are an integral component of the hypothalamic‐pituitary‐adrenal axis which governs the neuroendocrine response to stress. Corticotrophs display predominantly single spike activity under basal conditions that tran...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Duncan, Peter J., Şengül, Sevgi, Tabak, Joël, Ruth, Peter, Bertram, Richard, Shipston, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Renal and endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358680/
https://ncbi.nlm.nih.gov/pubmed/25615909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2015.284471
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