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The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

The human PYHIN proteins, AIM2, IFI16, IFIX, and MNDA, are critical regulators of immune response, transcription, apoptosis, and cell cycle. However, their protein interactions and underlying mechanisms remain largely uncharacterized. Here, we provide the interaction network for all PYHIN proteins a...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Diner, Benjamin A, Li, Tuo, Greco, Todd M, Crow, Marni S, Fuesler, John A, Wang, Jennifer, Cristea, Ileana M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358659/
https://ncbi.nlm.nih.gov/pubmed/25665578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145808
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