Associations between human aldosterone synthase CYP11B2 (-344T/C) gene polymorphism and antihypertensive response to valsartan in Chinese patients with essential hypertension

Aldosterone synthase is a mitochondrial enzyme that catalyzes the conversion of 11-deoxycorticosterone to the potent mineralocorticoid aldosterone. The gene encoding aldosterone synthase, CYP11B2, is associated with essential hypertension. But if the genetic variations in aldosterone synthesis could...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Ji, Xu, Qi, Hua, Li, Dong-Bao, Liu, Rong-Kun, Zheng, Yang, Chen, Hai-Ling, Guo, Jin-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358565/
https://ncbi.nlm.nih.gov/pubmed/25785110
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