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The yin and yang of kidney development and Wilms’ tumors

Wilms’ tumor, or nephroblastoma, is the most common pediatric renal cancer. The tumors morphologically resemble embryonic kidneys with a disrupted architecture and are associated with undifferentiated metanephric precursors. Here, we discuss genetic and epigenetic findings in Wilms’ tumor in the con...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Hohenstein, Peter, Pritchard-Jones, Kathy, Charlton, Jocelyn
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358399/
https://ncbi.nlm.nih.gov/pubmed/25737276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.256396.114
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