A Novel Mechanism of Regulating the ATPase VPS4 by Its Cofactor LIP5 and the Endosomal Sorting Complex Required for Transport (ESCRT)-III Protein CHMP5

Disassembly of the endosomal sorting complex required for transport (ESCRT) machinery from biological membranes is a critical final step in cellular processes that require the ESCRT function. This reaction is catalyzed by VPS4, an AAA-ATPase whose activity is tightly regulated by a host of proteins,...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Vild, Cody J., Li, Yan, Guo, Emily Z., Liu, Yuan, Xu, Zhaohui
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358147/
https://ncbi.nlm.nih.gov/pubmed/25637630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.616730
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