Disrupted-in-schizophrenia 1 (DISC1) Regulates Dysbindin Function by Enhancing Its Stability

Dysbindin and DISC1 are schizophrenia susceptibility factors playing roles in neuronal development. Here we show that the physical interaction between dysbindin and DISC1 is critical for the stability of dysbindin and for the process of neurite outgrowth. We found that DISC1 forms a complex with dys...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Lee, Seol-Ae, Kim, Seong-Mo, Suh, Bo Kyoung, Sun, Hwa-Young, Park, Young-Un, Hong, Ji-Ho, Park, Cana, Nguyen, Minh Dang, Nagata, Koh-ichi, Yoo, Joo-Yeon, Park, Sang Ki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Neurobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358130/
https://ncbi.nlm.nih.gov/pubmed/25635053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614750
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