Disrupted-in-schizophrenia 1 (DISC1) Regulates Dysbindin Function by Enhancing Its Stability

Dysbindin and DISC1 are schizophrenia susceptibility factors playing roles in neuronal development. Here we show that the physical interaction between dysbindin and DISC1 is critical for the stability of dysbindin and for the process of neurite outgrowth. We found that DISC1 forms a complex with dys...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Lee, Seol-Ae, Kim, Seong-Mo, Suh, Bo Kyoung, Sun, Hwa-Young, Park, Young-Un, Hong, Ji-Ho, Park, Cana, Nguyen, Minh Dang, Nagata, Koh-ichi, Yoo, Joo-Yeon, Park, Sang Ki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358130/
https://ncbi.nlm.nih.gov/pubmed/25635053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614750
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