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G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes

Some G protein-coupled receptors (GPCRs), in addition to activating heterotrimeric G proteins in the plasma membrane, appear to elicit a “second wave” of G protein activation after ligand-induced internalization. We briefly summarize evidence supporting this view and then discuss what is presently k...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Tsvetanova, Nikoleta G., Irannejad, Roshanak, von Zastrow, Mark
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358092/
https://ncbi.nlm.nih.gov/pubmed/25605726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.617951
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