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Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study

Ursodeoxycholic acid and its main conjugate glycoursodeoxycholic acid are bile acids with neuroprotective properties. Our previous studies demonstrated their anti-apoptotic, anti-inflammatory, and antioxidant properties in neural cells exposed to elevated levels of unconjugated bilirubin (UCB) as in...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Palmela, Inês, Correia, Leonor, Silva, Rui F. M., Sasaki, Hiroyuki, Kim, Kwang S., Brites, Dora, Brito, Maria A.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358072/
https://ncbi.nlm.nih.gov/pubmed/25821432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00080
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