Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes

Genotypic methods for drug susceptibility testing of Mycobacterium tuberculosis are desirable to speed the diagnosis and proper therapy of tuberculosis (TB). However, the numbers of genes and polymorphisms implicated in resistance have proliferated, challenging diagnostic design. We developed a micr...

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Foilsithe in:mBio
Main Authors: Pholwat, Suporn, Liu, Jie, Stroup, Suzanne, Gratz, Jean, Banu, Sayera, Rahman, S. M. Mazidur, Ferdous, Sara Sabrina, Foongladda, Suporn, Boonlert, Duangjai, Ogarkov, Oleg, Zhdanova, Svetlana, Kibiki, Gibson, Heysell, Scott, Houpt, Eric
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Microbiology 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357996/
https://ncbi.nlm.nih.gov/pubmed/25714709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02273-14
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