Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes

Genotypic methods for drug susceptibility testing of Mycobacterium tuberculosis are desirable to speed the diagnosis and proper therapy of tuberculosis (TB). However, the numbers of genes and polymorphisms implicated in resistance have proliferated, challenging diagnostic design. We developed a micr...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Pholwat, Suporn, Liu, Jie, Stroup, Suzanne, Gratz, Jean, Banu, Sayera, Rahman, S. M. Mazidur, Ferdous, Sara Sabrina, Foongladda, Suporn, Boonlert, Duangjai, Ogarkov, Oleg, Zhdanova, Svetlana, Kibiki, Gibson, Heysell, Scott, Houpt, Eric
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357996/
https://ncbi.nlm.nih.gov/pubmed/25714709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02273-14
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