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Novel Functions of (p)ppGpp and Cyclic di-GMP in Mycobacterial Physiology Revealed by Phenotype Microarray Analysis of Wild-Type and Isogenic Strains of Mycobacterium smegmatis

The bacterial second messengers (p)ppGpp and bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) regulate important functions, such as transcription, virulence, biofilm formation, and quorum sensing. In mycobacteria, they regulate long-term survival during starvation, pathogenicity, and dormancy. Recently, a...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Gupta, Kuldeepkumar Ramnaresh, Kasetty, Sanjay, Chatterji, Dipankar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357947/
https://ncbi.nlm.nih.gov/pubmed/25636840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03999-14
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