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Integration-free Methods for Generating Induced Pluripotent Stem Cells

Induced pluripotent stem (iPS) cells can be generated from mouse or human fibroblasts by exogenous expression of four factors, Oct4, Sox2, Klf4 and c-Myc, and hold great potential for transplantation therapies and regenerative medicine. However, use of retroviral vectors during iPS cell generation h...

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Bibliographic Details
Published in:Genomics Proteomics Bioinformatics
Main Authors: Zhou, Yi-ye, Zeng, Fanyi
Format: Artigo
Language:Inglês
Published: Elsevier 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357834/
https://ncbi.nlm.nih.gov/pubmed/24121200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2013.09.008
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