Extensive Genomic Variability of Knops Blood Group Polymorphisms Is Associated with Sickle Cell Disease in Africa

Sickle cell disease (SCD) is a multisystem disorder characterized by chronic hemolytic anemia, vaso-occlusive crises, and marked variability in disease severity. Patients require transfusions to manage disease complications, with complements, directed by complement regulatory genes (CR1) and its pol...

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Bibliografiske detaljer
Udgivet i:Evol Bioinform Online
Main Authors: Duru, Kimberley C, Noble, Jenelle A, Guindo, Aldiouma, Yi, Li, Imumorin, Ikhide G, Diallo, Dapa A, Thomas, Bolaji N
Format: Artigo
Sprog:Inglês
Udgivet: Libertas Academica 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357628/
https://ncbi.nlm.nih.gov/pubmed/25788827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/EBO.S23132
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