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Profile of atacicept and its potential in the treatment of systemic lupus erythematosus

The importance of B cell activating factors in the generation of autoantibodies in patients with systemic lupus erythematosus (SLE) is now recognized. The two key factors, known as BAFF and APRIL, produced by a variety of cells including monocytes, dendritic cells and T cells, also help to regulate...

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Publicat a:Drug Des Devel Ther
Autors principals: Cogollo, Estafania, Silva, Marta Amaral, Isenberg, David
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357613/
https://ncbi.nlm.nih.gov/pubmed/25834391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S71276
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