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Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases

Breast cancer survival rates decrease from 99% for patients with local disease to 25% for those with distant metastases. Matrix metalloproteinases (MMPs), including MMP2, are associated with metastatic progression. We found that loss of host MMP2 reduces the proliferation of experimental metastases...

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Détails bibliographiques
Publié dans:J Pathol
Auteurs principaux: Bates, A.L., Pickup, M.W., Hallett, M.A., Dozier, E.A., Thomas, S., Fingleton, B.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357558/
https://ncbi.nlm.nih.gov/pubmed/25469981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4493
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