Roles of Intramolecular and Intermolecular Interactions in Functional Regulation of the Hsp70 J-protein Co-chaperone Sis1

Unlike other Hsp70 molecular chaperones, those of the eukaryotic cytosol have four residues, EEVD, at their C-termini. EEVD(Hsp70) binds adaptor proteins of the Hsp90 chaperone system and mitochondrial membrane preprotein receptors, thereby facilitating processing of Hsp70-bound clients through prot...

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發表在:J Mol Biol
Main Authors: Yu, Hyun Young, Ziegelhoffer, Thomas, Osipiuk, Jerzy, Ciesielski, Szymon J., Baranowski, Maciej, Zhou, Min, Joachimiak, Andrzej, Craig, Elizabeth A.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357533/
https://ncbi.nlm.nih.gov/pubmed/25687964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.02.007
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