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Fertility and apparent genetic anticipation in Lynch syndrome

Genetic anticipation is the phenomenon in which age of onset of an inherited disorder decreases in successive generations. Inconsistent evidence suggests that this occurs in Lynch syndrome. A possible cause for apparent anticipation is fecundity bias, which occurs if the disease adversely affects fe...

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Détails bibliographiques
Publié dans:Fam Cancer
Auteurs principaux: Stupart, Douglas, Win, Aung Ko, Jenkins, Mark, Winship, Ingrid M., Goldberg, Paul, Ramesar, Rajkumar
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357528/
https://ncbi.nlm.nih.gov/pubmed/24677027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-014-9714-7
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