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A Mouse Model of L-2-Hydroxyglutaric Aciduria, a Disorder of Metabolite Repair
The purpose of the present work was to progress in our understanding of the pathophysiology of L-2-hydroxyglutaric aciduria, due to a defect in L-2-hydroxyglutarate dehydrogenase, by creating and studying a mouse model of this disease. L-2-hydroxyglutarate dehydrogenase-deficient mice (l2hgdh (-/-))...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357467/ https://ncbi.nlm.nih.gov/pubmed/25763823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119540 |
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