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Differential Effect of Phosphorylation-Defective Survivin on Radiation Response in Estrogen Receptor-Positive and -Negative Breast Cancer

Survivin is a key member of the inhibitor of apoptosis protein family, and is considered a promising therapeutic target due to its universal overexpression in cancers. Survivin is implicated in cellular radiation response through its role in apoptosis, cell division, and DNA damage response. In the...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Debeb, Bisrat G., Smith, Daniel L., Li, Li, Larson, Richard, Xu, Wei, Woodward, Wendy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357387/
https://ncbi.nlm.nih.gov/pubmed/25763854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120719
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