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Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices

Historically, it has been difficult to generate accurate and reproducible protein gradients for studies of interactions between cells and extracellular matrix. Here we demonstrate a method for rapid patterning of protein gradients using computer-driven hydrodynamic focusing in a simple microfluidic...

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Detalhes bibliográficos
Publicado no:Lab Chip
Main Authors: Georgescu, Walter, Jourquin, Jerome, Estrada, Lourdes, Anderson, Alexander R. A., Quaranta, Vito, Wikswo, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357342/
https://ncbi.nlm.nih.gov/pubmed/18231661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b716203k
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