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Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear

The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic chick. The chicken homolog of Numb is expresse...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Eddison, Mark, Weber, Sara J., Ariza-McNaughton, Linda, Lewis, Julian, Daudet, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357303/
https://ncbi.nlm.nih.gov/pubmed/25814931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00074
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