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Cooperative interactions between the interleukin 2 receptor alpha and beta chains alter the interleukin 2-binding affinity of the receptor subunits.

The interleukin 2 (IL-2) receptor (IL-2R) is a multisubunit receptor that includes three major IL-2 binding subunits, the IL-2R alpha, beta, and gamma chains. We have detected and analyzed cooperative interactions between the IL-2R alpha and beta chains (IL-2R alpha and IL-2R beta, respectively) in...

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Detalles Bibliográficos
Main Authors: Roessler, E, Grant, A, Ju, G, Tsudo, M, Sugamura, K, Waldmann, T A
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC43573/
https://ncbi.nlm.nih.gov/pubmed/8159750
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