DDR-mediated crosstalk between DNA-damaged cells and their microenvironment

The DNA damage response (DDR) is an evolutionarily conserved signaling cascade that senses and responds to double-strand DNA breaks by organizing downstream cellular events, ranging from appropriate DNA repair to cell cycle checkpoints. In higher organisms, the DDR prevents neoplastic transformation...

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Udgivet i:Front Genet
Main Authors: Malaquin, Nicolas, Carrier-Leclerc, Audrey, Dessureault, Mireille, Rodier, Francis
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357297/
https://ncbi.nlm.nih.gov/pubmed/25815006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00094
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