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Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus
The typical archaeal MCM exhibits helicase activity independently in vitro. This study characterizes MCM from the euryarchaeon Picrophilus torridus. While PtMCM hydrolyzes ATP in DNA-independent manner, it displays very poor ability to unwind DNA independently, and then too only under acidic conditi...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356968/ https://ncbi.nlm.nih.gov/pubmed/25762096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09057 |
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