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Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus

The typical archaeal MCM exhibits helicase activity independently in vitro. This study characterizes MCM from the euryarchaeon Picrophilus torridus. While PtMCM hydrolyzes ATP in DNA-independent manner, it displays very poor ability to unwind DNA independently, and then too only under acidic conditi...

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書目詳細資料
發表在:Sci Rep
Main Authors: Goswami, Kasturi, Arora, Jasmine, Saha, Swati
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356968/
https://ncbi.nlm.nih.gov/pubmed/25762096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09057
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