Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways

AIM: To investigate the efficacy and molecular mechanisms of induced heme oxygenase (HO)-1 in protecting liver from warm ischemia/reperfusion (I/R) injury. METHODS: Partial warm ischemia was produced in the left and middle hepatic lobes of SD rats for 75 min, followed by 6 h of reperfusion. Rats wer...

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Veröffentlicht in:World J Gastroenterol
Hauptverfasser: Huang, Han-Fei, Zeng, Zhong, Wang, Kun-Hua, Zhang, Hai-Yan, Wang, Shuai, Zhou, Wen-Xiang, Wang, Zhan-Bo, Xu, Wang-Gang, Duan, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Baishideng Publishing Group Inc 2015
Schlagworte:
Basic Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356913/
https://ncbi.nlm.nih.gov/pubmed/25780291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i10.2937
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