Depot Medroxyprogesterone Acetate in Combination with a Twice-Daily Lopinavir-Ritonavir-Based Regimen in HIV-Infected Women Showed Effective Contraception and a Lack of Clinically Significant Interactions, with Good Safety and Tolerability: Results of the ACTG 5283 Study

We conducted an open-label, steady-state pharmacokinetic (PK) study of drug-drug interactions between depot medroxyprogesterone acetate (DMPA) and twice-daily lopinavir (LPV) plus low-dose ritonavir (RTV) (LPV/r) among 24 HIV-infected women and compared the results to those for HIV-infected women re...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Luque, Amneris E., Cohn, Susan E., Park, Jeong-Gun, Cramer, Yoninah, Weinberg, Adriana, Livingston, Elizabeth, Klingman, Karin L., Aweeka, Francesca, Watts, D. Heather
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356823/
https://ncbi.nlm.nih.gov/pubmed/25624326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04701-14
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