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Safety and Pharmacokinetics of Isavuconazole as Antifungal Prophylaxis in Acute Myeloid Leukemia Patients with Neutropenia: Results of a Phase 2, Dose Escalation Study

Isavuconazole is a novel broad-spectrum triazole antifungal agent. This open-label dose escalation study assessed the safety and pharmacokinetics of intravenous isavuconazole prophylaxis in patients with acute myeloid leukemia who had undergone chemotherapy and had preexisting/expected neutropenia....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cornely, Oliver A., Böhme, Angelika, Schmitt-Hoffmann, Anne, Ullmann, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356760/
https://ncbi.nlm.nih.gov/pubmed/25624327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04569-14
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