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Towards a commercial process for the manufacture of genetically modified T cells for therapy

The recent successes of adoptive T-cell immunotherapy for the treatment of hematologic malignancies have highlighted the need for manufacturing processes that are robust and scalable for product commercialization. Here we review some of the more outstanding issues surrounding commercial scale manufa...

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Опубликовано в: :Cancer Gene Ther
Главные авторы: Kaiser, A D, Assenmacher, M, Schröder, B, Meyer, M, Orentas, R, Bethke, U, Dropulic, B
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356749/
https://ncbi.nlm.nih.gov/pubmed/25613483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2014.78
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