Examining the Feasibility of Clinical Grade CD271(+) Enrichment of Mesenchymal Stromal Cells for Bone Regeneration

INTRODUCTION: Current clinical trials utilize mesenchymal stromal cells (MSCs) expanded in culture, however these interventions carry considerable costs and concerns pertaining to culture-induced losses of potency. This study assessed the feasibility of new clinical-grade technology to obtain uncult...

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Pubblicato in:PLoS One
Autori principali: Cuthbert, Richard J., Giannoudis, Peter V., Wang, Xiao N., Nicholson, Lindsay, Pawson, David, Lubenko, Anatole, Tan, Hiang B., Dickinson, Anne, McGonagle, Dennis, Jones, Elena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356586/
https://ncbi.nlm.nih.gov/pubmed/25760857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117855
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