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Subtherapeutic concentrations of first-line anti-TB drugs in South African children treated according to current guidelines: the PHATISA study

OBJECTIVES: There is a paucity of evidence regarding the optimal dosing of anti-TB drugs in children. The aim of this study was to identify the pharmacokinetic parameters of first-line anti-TB drugs and the concentrations achieved after implementation of the 2010 WHO-recommended paediatric dosages....

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Hiruy, Hiwot, Rogers, Zoe, Mbowane, Chris, Adamson, John, Ngotho, Lihle, Karim, Farina, Gumbo, Tawanda, Bishai, William, Jeena, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356201/
https://ncbi.nlm.nih.gov/pubmed/25505005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku478
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