Vitamin B(12) insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

BACKGROUND: The dietary supply of methyl donors such as folate, vitamin B(12), betaine, methionine, and choline is essential for normal growth, development, and physiological functions through the life course. Both human and animal studies have shown that vitamin B(12) deficiency is associated with...

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Detaylı Bibliyografya
Yayımlandı:Clin Epigenetics
Asıl Yazarlar: Adaikalakoteswari, Antonysunil, Finer, Sarah, Voyias, Philip D, McCarthy, Ciara M, Vatish, Manu, Moore, Jonathan, Smart-Halajko, Melissa, Bawazeer, Nahla, Al-Daghri, Nasser M, McTernan, Philip G, Kumar, Sudhesh, Hitman, Graham A, Saravanan, Ponnusamy, Tripathi, Gyanendra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356060/
https://ncbi.nlm.nih.gov/pubmed/25763114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0046-8
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