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Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system

BACKGROUND: We have previously shown that hyperuricemia plays an important role in the vascular complications of insulin resistance (IR). Here we investigated the effect of xanthine oxidase (XO) inhibition on the cardiac complications of IR. METHODS: IR was induced in rats by a high fructose high fa...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: El-Bassossy, Hany M, Watson, Malcolm L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355989/
https://ncbi.nlm.nih.gov/pubmed/25889404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0445-9
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