Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.

The Cl- secretory pathway that is defective in cystic fibrosis (CF) can be bypassed by an alternative pathway for Cl- transport that is activated by extracellular nucleotides. Accordingly, the P2 receptor that mediates this effect is a therapeutic target for improving Cl- secretion in CF patients. I...

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Main Authors: Parr, C E, Sullivan, D M, Paradiso, A M, Lazarowski, E R, Burch, L H, Olsen, J C, Erb, L, Weisman, G A, Boucher, R C, Turner, J T
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43559/
https://ncbi.nlm.nih.gov/pubmed/8159738
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