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Liquid Chromatographic Method for Irinotecan Estimation: Screening of P-gp Modulators

The present work is aimed to develop a simple, sensitive, robust and reliable HPLC method for the estimation of irinotecan in the physiological media in order to assess the permeability profile of irinotecan, using the everted gut sac, in the presence of various P-gp modulators. Separation was achie...

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Publicado en:Indian J Pharm Sci
Autores principales: Tariq, M., Negi, L. M., Talegaonkar, Sushama, Ahmad, F. J., Iqbal, Zeenat, Khan, A. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355877/
https://ncbi.nlm.nih.gov/pubmed/25767314
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