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CXC Chemokines Function as a Rheostat for Hepatocyte Proliferation and Liver Regeneration

BACKGROUND: Our previous in vitro studies have demonstrated dose-dependent effects of CXCR2 ligands on hepatocyte cell death and proliferation. In the current study, we sought to determine if CXCR2 ligand concentration is responsible for the divergent effects of these mediators on liver regeneration...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wilson, Gregory C., Kuboki, Satoshi, Freeman, Christopher M., Nojima, Hiroyuki, Schuster, Rebecca M., Edwards, Michael J., Lentsch, Alex B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355613/
https://ncbi.nlm.nih.gov/pubmed/25756662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120092
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