CXC Chemokines Function as a Rheostat for Hepatocyte Proliferation and Liver Regeneration

BACKGROUND: Our previous in vitro studies have demonstrated dose-dependent effects of CXCR2 ligands on hepatocyte cell death and proliferation. In the current study, we sought to determine if CXCR2 ligand concentration is responsible for the divergent effects of these mediators on liver regeneration...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wilson, Gregory C., Kuboki, Satoshi, Freeman, Christopher M., Nojima, Hiroyuki, Schuster, Rebecca M., Edwards, Michael J., Lentsch, Alex B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355613/
https://ncbi.nlm.nih.gov/pubmed/25756662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120092
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