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A Kinetic Study of the Main Guaco Metabolites Using Syrup Formulation and the Identification of an Alternative Route of Coumarin Metabolism in Humans

For decades guaco species have been empirically used for the treatment of respiratory diseases. However, studies have shown that the toxic and therapeutic effects of the main guaco metabolites are dose-dependent, and none clinical study was done to evaluate the behavior of these substances in humans...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gasparetto, João Cleverson, Peccinini, Rosângela Gonçalves, de Francisco, Thais Martins Guimarães, Cerqueira, Letícia Bonâncio, Campos, Francinete Ramos, Pontarolo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355590/
https://ncbi.nlm.nih.gov/pubmed/25757073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118922
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