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Metabolic effects of newly synthesized phosphodiesterase-3 inhibitor 6-[4-(4-methylpiperidin-1-yl)-4-oxobutoxy]-4-methylquinolin-2(1H)-one on rat adipocytes

BACKGROUND: Clinical use of selective PDE3 inhibitors as cardiotonic agents is limited because of their chronotropic and lipolytic side effects. In our previous work, we synthesized a new PDE3 inhibitor named MC2 (6-[4-(4-methylpiperidin-1-yl)-4-oxobutoxy]-4-methylquinolin-2(1H)-one) which produced...

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Publicado no:Daru
Main Authors: Alinejad, Bagher, Shafiee-Nick, Reza, Sadeghian, Hamid, Ghorbani, Ahmad
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355504/
https://ncbi.nlm.nih.gov/pubmed/25880831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-015-0100-2
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