HNRNP G and HTRA2-BETA1 regulate estrogen receptor alpha expression with potential impact on endometrial cancer

BACKGROUND: Estrogen receptor alpha (ERa/ESR1) expression is regulated by alternative splicing. Its most frequently detectable exon7 skipping isoform (ERaD7) is a dominant negative variant. Elevated expression of ERaD7 was already detected in endometrial cancer (EC), while its potential prognostic s...

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Pubblicato in:BMC Cancer
Autori principali: Hirschfeld, Marc, Ouyang, Yi Qin, Jaeger, Markus, Erbes, Thalia, Orlowska-Volk, Marzenna, zur Hausen, Axel, Stickeler, Elmar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355463/
https://ncbi.nlm.nih.gov/pubmed/25884434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1088-1
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