T-cell reprogramming through targeted CD4-coreceptor and T-cell receptor expression on maturing thymocytes by latent Circoviridae family member porcine circovirus type 2 cell infections in the thymus

Although porcine circovirus type 2 (PCV2)-associated diseases have been evaluated for known immune evasion strategies, the pathogenicity of these viruses remained concealed for decades. Surprisingly, the same viruses that cause panzootics in livestock are widespread in young, unaffected animals. Rec...

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Bibliographische Detailangaben
Veröffentlicht in:Emerg Microbes Infect
Hauptverfasser: Klausmann, Stefanie, Sydler, Titus, Summerfield, Artur, Lewis, Fraser I, Weilenmann, Roseline, Sidler, Xaver, Brugnera, Enrico
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355439/
https://ncbi.nlm.nih.gov/pubmed/26038767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2015.15
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