Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice

INTRODUCTION: Previous studies in animal models of osteoarthritis suggest that alendronate (ALN) has antiresorptive and chondroprotective effects, and can reduce osteophyte formation. However, these studies used non-physiologic injury methods, and did not investigate early time points during which b...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Khorasani, Mohammad S, Diko, Sindi, Hsia, Allison W, Anderson, Matthew J, Genetos, Damian C, Haudenschild, Dominik R, Christiansen, Blaine A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355375/
https://ncbi.nlm.nih.gov/pubmed/25888819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0546-0
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