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Identification of the Base-Pairing Requirements for Repression of hctA Translation by the Small RNA IhtA Leads to the Discovery of a New mRNA Target in Chlamydia trachomatis

The non-coding small RNA, IhtA expressed by the obligate intracellular human pathogen Chlamydia trachomatis modulates the translation of HctA, a key protein involved in replicative to infectious cell type differentiation. Using a combination of bioinformatics and mutagenesis we sought to identify th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Grieshaber, Nicole A., Tattersall, Jeremiah S., Liguori, Johella, Lipat, Joseph N., Runac, Justin, Grieshaber, Scott S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355289/
https://ncbi.nlm.nih.gov/pubmed/25756658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116593
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